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Qiang-Zhong Pi

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Review Jul 2026

Multifactorial Regulation of Inflammatory Bone Loss in Chronic Inflammatory and Immune-Associated Disorders: Osteoimmune Mechanisms and Translational Prospects of Natural Small Molecules

The osteoimmune mechanisms through which persistent inflammation disrupts coupled bone remodeling are synthesized, with emphasis on RANKL-dependent osteoclastogenesis, suppressed osteoblast-supportive signaling, cytokine networks, immune-cell plasticity, and lesion microenvironment.

Juhao Pi, Bo-Lei Li, Qiang-Zhong Pi et al. · 0 citations

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