Sep 2026
Age-associated chromatin repression of Hippo-Yap signaling drives oogonial stem cell decline in chicken
It is shown that OSC number and proliferative capacity decline significantly from pre-laying to late-laying stages, accompanied by increased follicular atresia, and epigenetic repression of the Hippo–YAP axis suppresses OSC proliferation through epigenetic repression of the Hippo–YAP axis.
Jia-Hui Wei, Jin Wang, Hong-Cai Sun et al.
· Functional & Integrative Gen... · 0 citations