A Meta-Analysis of Animal Experiments on CRISPR-Cas9 Gene Editing for Hereditary Blood Disorders: Efficacy Assessment and Challenges in Hematopoietic System Reconstitution
Background: Hereditary blood disorders lack curative therapies. As an emerging therapeutic strategy, the efficacy and safety of CRISPR-Cas9 gene editing technology in preclinical animal models require systematic integration and evaluation. This study, through a meta-analysis, aims to comprehensively evaluate the editin...