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Author

R. Cruces

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Open access Oct 2026

Assessing the Functional-Structural Reorganization of Connector Hubs in Temporal Lobe Epilepsy

Temporal lobe epilepsy (TLE) is associated with altered functional connectivity, yet its effects on connector hubs, regions supporting long-range and inter-network communication, remain poorly understood. We used SParsity-based Analysis of Reliable k-hubness to characterize connector hub reorganization in unilateral TL...

Arielle Dascal, Édouard Delaire, A. Ngo et al. · 0 citations
Open access Sep 2026

HIPPOCAMPAL TAU-RELATED SIGNAL INDEXES HYPEREXCITABILITY AND NREM SLEEP–MEMORY DYSFUNCTION IN TEMPORAL LOBE EPILEPSY

It is suggested that hippocampal 18F-MK6240 uptake may represent a candidate marker of circuit vulnerability associated with NREM sleep-memory dysfunction in TLE, warranting validation in larger longitudinal studies.

Thaera Arafat, Katharina Schiller, J. Lam et al. · 0 citations
Open access Aug 2026

Topographic-prognostic gradients of cortical hypometabolism in temporal lobe epilepsy

A hypometabolic gradient is identified in TLE, which covaries with cytoarchitectonic organization, microstructural changes, and hippocampal-neocortical interactions and provides a biologically grounded framework for precise surgical planning, emphasizing that targeting severe hypometabolism may optimize prognosis.

J. Mo, F. Fadaie, J. Lam et al. · 0 citations

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