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HIPPOCAMPAL TAU-RELATED SIGNAL INDEXES HYPEREXCITABILITY AND NREM SLEEP–MEMORY DYSFUNCTION IN TEMPORAL LOBE EPILEPSY

Thaera Arafat Katharina Schiller J. Lam N. von Ellenrieder Zheng-Chen Cai J. DeKraker F. Fadaie Viviane Sziklas Joelle Crane R. Cruces R. Hopewell C. Hsiao G. Massarweh J. Soucy Kjell Erlandsson S. A. Hosseini T. Chan Eliane Kobayashi Pedro Rosa-Neto A. Bernasconi N. Bernasconi Matthias J. Koepp J. Gotman B. Bernhardt
Sep 2026 · bioRxiv · 0 citations
Biology

TL;DR

It is suggested that hippocampal 18F-MK6240 uptake may represent a candidate marker of circuit vulnerability associated with NREM sleep-memory dysfunction in TLE, warranting validation in larger longitudinal studies.

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