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#gene editing Open access Sep 2026

Critical role for the TGF-β1/mTORC1 signaling axis in defining the transcriptional identity of CTHRC1+ pathologic fibroblasts

It is concluded that mTORC1 plays a key role in shaping the transcriptional identity of these fibroblasts, with implications for therapeutic inhibition of mTORC1 in fibrosis and cancer.

J. A. Wilson, Rachel Walters, G. Contento et al. · 0 citations
Review Open access Jul 2026

Future Directions in Stem Cells, Cell Therapy, and Bioengineering in Lung Biology and Diseases.

Improved ex vivo lung models to better capture cellular heterogeneity and biomechanics; using single-cell, spatial, and computational approaches to support translation into clinical practice; and innovative therapeutic strategies.

Lei Wang, Sarah Y Shin, J. Hook et al. · 0 citations

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