Review
Open access
Aug 2026
Macrocyclic peptides and peptidomimetics as modulators of protein-protein interactions.
This review comprehensively examines the biological significance of PPIs in human disease and details how MPPs effectively modulate historically undruggable targets, highlighting current synthetic strategies, peptide engineering platforms, and the clinical and preclinical status of leading MPP candidates, while weighin...
Rajesh Parmar, Vidit Shrivastava, Gurmeet Kaur et al.
· RSC Medicinal Chemistry · 0 citations