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Review Open access Sep 2026

Distinct Rb expression pattern in HPV-associated neuroendocrine carcinomas of the uterine cervix.

AIMS This study aimed to characterize high-risk human papillomavirus (HR-HPV) infection and the expression patterns of p16, Rb, p53 and cyclin D1 in uterine cervical neuroendocrine carcinomas (UCNECs). We also aimed to clarify the similarities and differences between UCNECs and pulmonary neuroendocrine carcinomas (NECs...

Nobuko Yasutake, Misato Komamizu, Takeshi Iwasaki et al. · 0 citations
Sep 2026

High-risk human papillomavirus infection and immunohistochemical expression patterns of p16 and Rb in primary and metastatic squamous cell carcinoma of the lung.

The p16+/Rb partial loss pattern was exclusively associated with metastatic HPV-related SCC, whereas primary lung SCC demonstrated distinct p16 and Rb expression profiles, suggesting a lower prevalence than previously reported.

Fumiya Narutomi, Hidetaka Yamamoto, Mikiko Hashisako et al. · 0 citations

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