Author

R. Melekoğlu

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Open access Sep 2026

Maternal-fetal adipokine remodeling in obesity-complicated pregnancies: associations with neonatal macrosomia and NICU requirement

Introduction Maternal obesity is associated with altered maternal–fetal adipokine profiles and adverse early neonatal outcomes. This study aimed to characterize maternal and fetal adipokine patterns across obesity severity groups and to evaluate their associations with macrosomia and neonatal intensive care unit (NICU)...

K. Aslaner, R. Melekoğlu, Ş. Yaşar et al. · Frontiers in Endocrinology · 0 citations

#protein folding Open access Oct 2026

Maternal Plasma Proteomic Signatures Distinguish Preeclampsia from Healthy Pregnancy but Not Early-Onset from Late-Onset Subtypes: A Leakage-Free Machine-Learning and Explainability Study

Early-onset (EOPE) and late-onset (LOPE) preeclampsia are clinically distinct, but their molecular differences are incompletely defined. Using a strictly leakage-free pipeline, we re-examined maternal plasma proteomes of EOPE, LOPE, and healthy pregnancy (HP) and asked whether the subtypes are separable at the proteome...

Ş. Yaşar, R. Melekoğlu, Nese Basak Turkmen et al. · International Journal of Mol... · 0 citations

Open access Sep 2026

Development of Novel Prenatal Prediction Models for Birth-Weight Estimation in Low-Risk Third-Trimester Pregnancies

Objective: Sonographic evaluation of the fetus and estimation of fetal weight are integral components of modern obstetric practice. Estimated fetal weight (EFW) plays a crucial role in predicting macrosomia, diagnosing intrauterine growth restriction, and monitoring fetal development. This study aimed to improve birth-...

Sevda Yeleç, R. Melekoğlu, Yusuf Kemal Arslan et al. · Biomedicines · 0 citations