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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

R. Sachdeva

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Open access Jul 2026

LINE-1 transposon derepression and epigenetic remodeling in Retinoblastoma

It is shown that retinoblastoma is associated with LINE-1 promoter hypomethylation, increased LINE-1 transcript expression, ORF1p accumulation, and preferential activation of selected LINE-1 loci, which is associated with altered expression of oncogenic signalling pathways and host factors involved in transposable elem...

Aman Verma, Sugam Kumar Patel, Akhil Varshney et al. · 0 citations

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