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Uncovering the long non-coding RNAs in Drosophila: Tissue specific expressions and functional roles in reproductive development
This review coalesces current knowledge on the abundance, mutational effects, and functional insights of lncRNAs in Drosophila testis and brain, highlighting their value as a model for deciphering conserved lncRNA biology and its implications for human reproductive health.
Design and evaluation of a novel peptide-EV complex for targeted Alzheimer's disease therapy.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that involves the formation of amyloid-β (Aβ) aggregates, and the development of targeted therapeutic strategies is needed. In the current work, we report the rational design of H102-CP05, a 22-residue chimeric peptide that integrates the β-sheet brea...