Open access
Sep 2026
Hippocampal/medial temporal sclerosis is associated with clinical severity, regional TDP-43, and hippocampal atrophy in Alzheimer disease
Alzheimer disease neuropathologic change (ADNC) does not fully explain clinical severity, suggesting important contributions from coexisting pathologies, and clinical severity therefore cannot be inferred from ADNC alone.
Preeti Sharma, Rajath Devappa, Sivaprakasam R. Saroja
· bioRxiv · 0 citations