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Author

R. Thomas

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Aug 2026

Multiomic and Spatial Profiling of Colorectal Tissue Reveals Viral Persistence and Immune Dysregulation in Long COVID

A tissue-based transcriptional environment in which SARS-CoV-2 activates innate myeloid immune signaling, driving chronic inflammation while simultaneously downregulating pathways responsible for immune-mediated clearance of infected cells is identified, including antigen presentation, phagocytosis, cytotoxic immune ce...

B. LaFranchi, David P. Maison, J. Vinden et al. · 0 citations
Open access Aug 2026

Tau reduction counteracts transcriptomic and behavioral abnormalities in an Alzheimer amyloid model

Tau reduction supports the potential benefits and safety of overall tau reduction and the hypothesis that even physiological forms of tau can allow pathogenic triggers such as AD-mutant APP and PS1 to elicit aberrant neuronal activities and synaptic degeneration.

Sara J. Knowles, Cathrine Sant, Pranav Nambiar et al. · 0 citations

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