RNA delivery to the corneal endothelium using charge-altering releasable transporters
A charge-altering releasable transporter (CART) that delivers RNA selectively to the corneal endothelium, a non-regenerative cell layer whose dysfunction underlies several blinding conditions and establishes CARTs as a platform for non-viral gene delivery to the eye, with the potential to treat corneal dystrophies and other vision disorders.
Sean K. Wang, Zhijian Li, Sahil H Shah et al.
· Science Advances · 0 citations