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Author

Richard E. Sutton

2 papers indexed here

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Review Open access Sep 2026

mRNA processing in cancer immunotherapy: emerging targets, resistance mechanisms, and therapeutic opportunities

Cancer immunotherapy has improved outcomes across many tumor types, but primary and acquired resistance, tumor heterogeneity and a shortage of safe targets remain unresolved. Part of this gap arises because tumor cells evade immune recognition not only through genomic mutation but also through post-transcriptional mRNA...

Y. Yukselten, Haseeb Ahmad, Mohammed Shoultout et al. · 0 citations
Open access Sep 2026

A Selective PanK3 Activator Restores Coenzyme A in Cellular and Mouse Models of Pantothenate Kinase-Associated Neurodegeneration.

Pantothenate kinase-associated neurodegeneration, PKAN, is a rare progressive neurodegenerative disorder associated with iron accumulation in the brain. The disease, which causes early immobility and often death by early adulthood, is caused by loss of function mutations in the human PANK2 gene, encoding a key enzyme i...

Jessica Regan, A. Pal, S. Gihaz et al. · 0 citations

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