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Author

Robert P. Giugliano

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Clinical trial Open access Jan 2026

Clinical Validation of a Point-of-Care Whole Blood Coagulometer in Patients on Factor Xa Inhibitors

ClotChek clotting times showed good sensitivity and specificity to identify meaningful anticoagulation among patients taking apixaban or rivaroxaban, and could aid physicians at the point of care in making therapeutic decisions in patients with adverse events associated with oral factor Xa inhibitors.

S. Bakhru, Jean M. Connors, Robert P. Giugliano et al. · 0 citations
Aug 2026

Incidence and Predictors of Extracranial Bleeding on Oral Anticoagulants for Stroke Prevention in Patients With Atrial Fibrillation: A COMBINE-AF Analysis.

Extracranial clinically relevant bleeding is common among patients with AF treated with OACs and may more accurately reflect the overall burden of bleeding than major bleeding alone, suggesting that additional unmeasured or unknown factors contribute to bleeding risk.

Deborah M. Siegal, Marc Carrier, M. Bahit et al. · 0 citations

Thrombosis and Haemostasis Clinical Validation of a Point-of-Care Whole Blood Coagulometer in Patients on Factor Xa Inhibitors

ClotChek clotting times showed good sensitivity and specificity to identify meaningful anticoagulation among patients taking apixaban or rivaroxaban, and could aid physicians at the point of care in making therapeutic decisions in patients with adverse events associated with oral factor Xa inhibitors.

S. Bakhru, Jean M. Connors, Robert P. Giugliano et al. · 0 citations
Open access Jul 2026

Contemporary patients with atrial fibrillation are not anticoagulated despite risks of stroke - Insights from GARDENIA

Perceived risk of bleeding was the leading cause for non-treatment with OACs in high-risk AF patients, and risk prediction modelling indicated that the benefits of anticoagulation in stroke and mortality reduction outweigh the risk of bleeding.

A. Kakkar, Marc P Bonaca, Robert P. Giugliano et al. · 0 citations

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