Protocol for quantification of AAV-CRISPR-mediated hepatic gene editing in mice.
Adeno associated viral (AAV) delivery of CRISPR-Cas9 enables efficient, targeted hepatic gene disruption composed of both small insertions and deletions (INDELs) and larger DNA structural variants (DNA-SVs), which are difficult to quantify. Here, we present a protocol for quantifying AAV-CRISPR-mediated gene editing in...
K. Jarrett, Rodrigo Baltazar-Nunez, Chloe Anne Borja et al.
· STAR Protocols · 0 citations