Author

Rohan S. Eapen

2 papers indexed here

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2027

Generating and Evaluating New Chemigenetic Fluorescent Biosensors for Protein Kinase A Based on Synthetic Organic Fluorophores.

This chapter provides a practical workflow for the implementation of intensity-based chemigenetic biosensors, centered around the HaloAKAR2.1 scaffold, a biosensor for protein kinase A activity.

Rohan S. Eapen, Michelle S. Frei · Methods in molecular biology · 0 citations

Open access Oct 2026

A chemigenetic fluorescence lifetime-based biosensor for imaging of ERK activity

Extracellular signal-regulated kinase (ERK) governs many cellular processes, and its spatiotemporal activity dynamics are important for downstream signaling specificity. Existing fluorescent ERK activity biosensors, however, fall short in enabling spectrally multiplexed, spatially resolved, or deep tissue measurements....

Elias Dressler, Rohan S. Eapen, Dennis Pellanda et al. · bioRxiv · 0 citations