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Author

Ronald B. Tjalkens

2 papers indexed here

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Open access Sep 2026

ALDH1/2 deficiency modulates dieldrin-induced dopaminergic neurodegeneration and reactive glial morphometry in male mice

The etiology of Parkinson’s disease (PD) is associated with exposure to environmental contaminants, including the organochlorine pesticide dieldrin. This is thought to occur through induction of oxidative damage and dysregulation of dopamine homeostasis via impairment of aldehyde dehydrogenase (ALDH) enzymes, resulting...

Omar A. Yanouri, Adam J. Schuller, Savannah M. Rocha et al. · 0 citations
Aug 2026

Infection with Western equine encephalitis virus causes severe regional glial reactivity and neurodegeneration in the hippocampus with progressive accumulation of amyloid-β.

A longitudinal assessment of hippocampal pathology following intranasal infection with McMillan WEEV defines a dynamic sequence of glial activation, lesion formation, and protein aggregation underlying WEEV-induced hippocampal neurotoxicity.

Aidan M. Briggs, Adam J. Schuller, Megan R. Hager et al. · 0 citations

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