Encapsulation-Activated Deep-NIR Triarylmethane Dyes via Steric Hindrance Engineering for Long-Circulating Fluorescence/Photoacoustic Dual-Modal Bioimaging
Abstract NIR-II fluorescence/photoacoustic dual-modal imaging offers complementary advantages in sensitivity and penetration depth. However, its efficacy is compromised by aggregation, nonspecific binding, and background interference, which persist even with polymeric encapsulation. To address these limitations, we rep...