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S. Ajdary

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Open access Oct 2026

An integrated immunoinformatics and experimental pipeline identifies an LCL-scaffolded OmpA loop 3 construct as a protective vaccine candidate against Acinetobacter baumannii.

Acinetobacter baumannii has emerged as a critical nosocomial pathogen due to its extensive antimicrobial resistance and limited treatment options, highlighting the urgent need for effective vaccines. In this study, we developed and evaluated a rationally engineered epitope-based vaccine targeting extracellular loop 3 o...

Seyyedeh Reyhaneh Banisaeed, I. Rasooli, T. Ghazanfari et al. · 0 citations
Open access Oct 2026

Impact of Leishmania RNA virus 2 on immune response and pathogenesis in Leishmania major-infected BALB/c mice

Leishmania RNA virus (LRV)1 has been associated with altered disease outcomes in cutaneous leishmaniasis (CL), but the role of LRV2 in Leishmania major ( L. major ) infection remains poorly understood. This study investigated the impact of LRV2-positive L. major (Lm-LRV2 + ) on disease progression and host...

F. Riazi-rad, A. Katebi, S. Pakzad et al. · 0 citations
Jul 2026

Growth‐Factor‐Free Bone Regeneration: A Chitosan/Mg‐Doped Hydroxyapatite Nanocomposite Scaffold Synergistically Activated by Icariin, Lithium Chloride, and Naringin

Chitosan/Mg‐HAp scaffolds enriched with icariin, lithium chloride, and naringin exhibit an advantageous combination of structural, mechanical, biological, and antimicrobial properties, and effectively promote bone regeneration without the need for expensive recombinant growth factors, highlighting their potential as ad...

Sahar Hefzollesan, H. Musayeva, Hamed Aghazadeh et al. · 0 citations
Jul 2026

Bioactive electrospun chitosan/magnesium-doped hydroxyapatite nanocomposite scaffold co-loaded with icariin, lithium chloride and naringin for enhanced osteogenesis, antibacterial activity and bone regeneration in vitro and in vivo

The bioactive chitosan/Mg-HAp nanocomposite scaffold effectively promotes bone regeneration by enhancing osteogenic signaling pathways and exhibits strong potential for bone tissue engineering applications.

S.M. Hefzollesan, H. Musayeva, Hamed Aghazadeh et al. · 0 citations

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