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In silico analysis of plastic additive-biological target interactions identified potential carcinogenic, reproductive, and neurological health hazards and revealed key molecular pathways underlying plastic additive-induced toxicity.
The chapter provides in-depth information on the role of HDAC inhibitors, which hold significant potential as disease-modifying agents in the treatment of Alzheimer's disease and explores various challenges such as off-target effects, restricted isoform specificity, and inadequate blood-brain barrier permeability.
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