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Author

S. Chan

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Review Open access Oct 2026

Genotype–phenotype analysis in 333 individuals with heterozygous variants in NFKB1

Our literature review included all currently published patients with NFKB1 variants. Variants were divided into subcohorts and classified into distinct variant classes. Correlative analyses were performed to search for genotype–phenotype correlations.

Sophia Marie Armbruster, Andrés Caballero-Oteyza, Oliver Bartsch et al. · 0 citations
#gene editing Open access Jul 2026

Prime editing enables drug-controllable T-cell therapies with clinical immunosuppression.

A multiplex prime-editing platform is developed that converts commonly used immunosuppressive drugs into tools for in vivo control of T-cell therapies via defined, pathway-specific drug resistance, enabling selective in vivo modulation in settings where immunosuppression cannot be withdrawn.

E. Bandala-Sanchez, Emma V. Petley, K. Ramsay et al. · 0 citations

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