Abstract Cellular plasticity is a central feature of malignant progression, allowing tumour cells to change identity during tumour evolution, therapeutic adaptation, and metastatic dissemination. This issue is especially acute in lung cancer, where the respiratory epithelium is intrinsically permissive to cell-state ch...
Julia S. Scott, C. Lutz, S. Preković· Biochemical Society Transact...· 0 citations
Immunity protection from macrophages is revealed as an adverse consequence of hormonal therapy in prostate cancer patients using a genome-wide co-culture CRISPR screen and positions tumor-intrinsic AR signaling as a bona fide immunomodulatory pathway.
Anniek Zaalberg, Audrey Lacoste, Emma Minnee et al.· Oncogene· 0 citations
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