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S. Preković

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Review Open access Oct 2026

Genes, fuel, and fate in lung cancer

Abstract Cellular plasticity is a central feature of malignant progression, allowing tumour cells to change identity during tumour evolution, therapeutic adaptation, and metastatic dissemination. This issue is especially acute in lung cancer, where the respiratory epithelium is intrinsically permissive to cell-state ch...

Julia S. Scott, C. Lutz, S. Preković · 0 citations
Open access Jul 2026

A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator

Immunity protection from macrophages is revealed as an adverse consequence of hormonal therapy in prostate cancer patients using a genome-wide co-culture CRISPR screen and positions tumor-intrinsic AR signaling as a bona fide immunomodulatory pathway.

Anniek Zaalberg, Audrey Lacoste, Emma Minnee et al. · 0 citations

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