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S. Smyth

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#protein folding Open access Sep 2026

Conformational ensembles of the disordered 4E‐BP2:eIF4E complex restrained by smFRET experiments

Full‐length atomistic conformational ensembles generated by IDPConformerGenerator and optimized by X‐EISDv2 workflow support a model of translation regulation in which the dynamic 4E‐BP2:eIF4E complex facilitates accessibility of regulatory sites of 4E‐BP2 when bound.

S. Smyth, Zi-Hao Liu, Thomas E. Tsangaris et al. · 0 citations

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