Open access
Sep 2026
TNFR1 expression on cancer cells mediates immune escape and an immunosuppressive microenvironment
This study provides evidence for a key role of TNFR1, as expressed by malignant cells, in orchestrating a pro-tumor immunosuppressive environment through secondary inflammatory mediators. Results highlight the relevance of interfering TNFα/TNFR1 in cancer immunotherapy.
Elixabet Bolaños, Lorena Cañas-Zabala, Irene Olivera et al.
· Journal of Experimental Medi... · 0 citations