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Author

Samantha E. Clark

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Review Sep 2026

Biological Embedding of Adverse Childhood Experiences: Neurobiological and Immune Mechanisms Linking Early-Life Stress to Addiction Vulnerability.

It is argued that integrating immune embedding with stress- reward recalibration may clarify one pathway by which ACEs confer SUD vulnerability and may inform trauma- informed, neurobiologically grounded approaches to prevention and treatment.

Samantha E. Clark, M. Monnig, Peter M. Monti · 0 citations

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