Author

Samuel A. Knoedler

2 papers indexed here

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Oct 2026

Frailty as a Predictor of Outcomes After Fibula Free Flap for Head and Neck Reconstruction: A Multi-Institutional Analysis Using the mFI-5.

BACKGROUND Chronological age inadequately reflects physiologic vulnerability in older adults undergoing complex reconstruction. Frailty, quantified by the 5-item Modified Frailty Index (mFI-5), may better stratify perioperative risk in fibula free flap (FFF) reconstruction for head and neck defects, but its impact rema...

Wei-Tee Jia, D. Matar, Lorenzo Puppi et al. · Microsurgery · 0 citations

#protein folding Open access Sep 2026

Hypoxia preconditioned serum (HPS) and platelet-rich plasma (PRP) promote proliferation, neurite network formation, and neurite elaboration in N2a cells

Findings identify HPS and PRP as biologically active secretomes with potential to support neuronal structural remodeling, warranting investigation in primary neuronal cultures and in vivo models of peripheral nerve regeneration.

Jun Jiang, D. Safa, Samuel A. Knoedler et al. · Frontiers in Bioengineering... · 0 citations