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Author

Santu Paul

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Aug 2026

Viral Protease Nsp5 Hijacks La Autoantigen to Orchestrate the Translation to Replication Transition in SARS-CoV-2

It is demonstrated that human La autoantigen (La protein) specifically binds to GCAC sequence near the initiator AUG within the 5’UTR of SARS-CoV-2 RNA promoting viral non-structural protein synthesis by cap independent translation, while suppressing replication early in infection.

Risabh Sahu, Harsha Raheja, S. N. Gagan Gaurav et al. · 0 citations

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