Saravanan Ravindran

ANALYTICAL QUALITY BY DESIGN-ASSISTED DEVELOPMENT AND VALIDATION OF A RAPID STABILITY-INDICATING GRADIENT ULTRA-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR SIMULTANEOUS ESTIMATION OF EMPAGLIFLOZIN, SACUBITRIL, AND VALSARTAN IN PHARMACEUTICAL DOSAGE FORMS

Objectives: Simultaneous estimation of empagliflozin, sacubitril, and valsartan in combined pharmaceutical formulations is analytically challenging due to their differing polarity, physicochemical properties, and chromatographic retention behavior. Conventional high-performance liquid chromatography methods often requi...

CARBON AND ENZYME-BASED NANOBUD FOR ENVIRONMENTAL SUSTAINABILITY IN PHARMACEUTICAL WASTEWATER TREATMENT

The widespread occurrence of pharmaceutical contaminants in water bodies has become a major environmental concern due to their persistence, bioaccumulation potential, and adverse effects on aquatic ecosystems and human health. Conventional wastewater treatment technologies often exhibit limited efficiency in removing t...

Synergistic Oxygen and Nitric Oxide Delivery Via an Immuno Instructive Silk Fibroin Hydrogel for Chronic Diabetic Wound Repair

Objective: Diabetic chronic wounds exhibit impaired healing due to persistent hypoxia, oxidative stress, infection, and dysregulated immune responses. Conventional wound dressings fail to address these complex pathological factors simultaneously. This study aimed to develop a multifunctional silk fibroin (SF) hydrogel...

Emerging Role of Human Organoids in Drug Discovery and Development: Current Advances and Challenges