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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Scott D. Ryan

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#protein folding Review Open access Sep 2026

From dynamic condensates to pathological assemblies: the phase behavior of tau and α-synuclein

Neurons rely on precise protein folding, trafficking, and turnover to maintain synaptic function. Disruption of proteostasis promotes misfolded proteins that impair axonal transport, mitochondrial function, and signalling, contributing to neuronal loss. Although neurodegeneration has traditionally focused on stable amy...

Suelen Camargo, Kevin Novelo, Scott D. Ryan · 0 citations
Sep 2026

Electrostatic Regulation of Alpha-Synuclein Membrane Binding Couples Conformational Release to Aggregation Kinetics

Misfolding and aggregation of α-synuclein (α-syn) are central to Parkinson’s disease (PD) pathology and are increasingly believed to be modulated by lipid-rich cellular environments. Electrostatic interactions between α-syn and anionic lipids play a key role in membrane binding and can significantly influence aggrega...

Mahdi Lavasani, Ping Lu, Shehani V. Siripala et al. · 0 citations

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