Author

Sean K. Whittier

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Open access Sep 2026

The pod components of the Shigella T3SS sorting platform accommodate multiple copies of Spa33 (SctQ)

The bacterial type III secretion system (T3SS) uses a membrane-embedded injectisome assembly to export effector proteins into host cells. While atomic-level structural details have been revealed for much of the T3SS apparatus, the model of the cytoplasmic sorting platform remains largely low-resolution. A central struc...

Sean K. Whittier, Shoichi Tachiyama, Samira Heydari et al. · PLoS Pathogens · 0 citations

#protein folding Open access Sep 2026

An intranasal bivalent vaccine induces antigen-specific humoral and Th1/Th17 cellular immunity and protects young and aged mice against MRSA and Pseudomonas aeruginosa skin and soft tissue infections

ABSTRACT Staphylococcus aureus (SA) and Pseudomonas aeruginosa (PA) are ESKAPE pathogens that are responsible for severe skin and soft tissue infections (SSTIs), particularly in the elderly and those with immunocompromising conditions. Rising rates of methicillin-resistant S. aureus (MRSA) and carbapenem-resistant PA h...

Suhrid Maiti, T. Lu, Zackary Dietz et al. · Infection and Immunity · 0 citations