Author

Sean P. Curran

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Open access Aug 2026

Form and function of actin impacts actin health and aging

How genetic and pharmacologic perturbations of actin structure and function influence lifespan and various hallmarks of aging in Caenorhabditis elegans is interrogated, providing a comprehensive and publicly accessible resource that maps, for the first time, how changes in actin integrity correlate with diverse aging p...

Maxim Averbukh, Hunter T. Nelson, Tiffany Wang et al. · iScience · 2 citations

Review Open access Sep 2026

Metabolic shifts driven by host-microbial interactions

This work focuses on microbial metabolism as a central organizing principle of host–microbiota symbiosis and discusses emerging therapeutic strategies that target microbial metabolic functions that position microbial metabolism as a tractable axis for modulating immunometabolism homeostasis and potentially mitigating m...

Tripti Nair, Nicole L. Stuhr, Brandy A. Weathers et al. · The FEBS Journal · 0 citations

Open access Aug 2026

Neuronal expression of bromodomain proteins alters neuronal health and peripheral protein homeostasis to promote longevity

It is shown that the neuronal expression of the chromatin reader BET-1 promotes longevity and resilience in C. elegans through signaling mechanisms involving master transcription factors HSF-1 and DAF-16 and neurotransmitter UNC-13.

Naibedya Dutta, Daniel Hicks, Edgar Esparza et al. · Genes & Development · 0 citations