Author

Sen-Yu Yao

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Open access Jul 2026

Clinical trial landscape of cell therapy for spinal cord injury: from integrated practices to future developments

Clinical trials for SCI were mapped to quantify patient demographic parameters, identify lineage-specific adverse-event patterns, evaluate objective motor and sensory efficacy outcomes, and analyze methodological trial designs to formulate concrete structural recommendations for future advanced-phase trials.

Jun Kang, Sen-Yu Yao, Song-Fu Zou et al. · BMC Medicine · 0 citations

Jul 2026

PLIN2-PGAM5-regulated lipid droplet-mitochondria contacts drive microglial neuroinflammation after spinal cord injury via fatty acid metabolic reprogramming.

The findings identify the PLIN2-PGAM5 as a critical metabolic-immune pathway and suggest that targeting organelle-contact-mediated metabolic reprogramming represents a potential therapeutic strategy for CNS injury.

Daoqiang Huang, Hong Li, Yiqian Luo et al. · Cell Death and Differentiati... · 2 citations