Author

S. Lee

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#protein folding Open access Sep 2026

Toxicological assessment of GenX in WPMY-1 normal prostate stromal cells: apoptotic responses, oxidative stress, and multi-pathway transcriptomic remodeling

GenX (ammonium perfluoro(2-methyl-3-oxahexanoate)) is an HFPO-DA-related PFAS replacement with emerging health concerns, yet its effects on prostate stromal cells remain poorly understood. This study investigated the cytotoxic, apoptotic, and oxidative effects of GenX in WPMY-1 human prostate stromal cells and characte...

Ji Won Park, Seon-Min Lee, Hye Jin Kim et al. · Applied Biological Chemistry · 0 citations

#protein folding Open access Aug 2026

Diesel particulate matter induces dose-dependent cytotoxicity, multi-faceted inflammation, MAPK activation, and oxidative stress in RAW 264.7 macrophages: an integrated transcriptomic and protein–protein interaction network analysis

Beyond classical inflammation, these integrated findings reveal coordinated network-level perturbations consistent with ferroptosis vulnerability, genome instability, paradoxical immune dysregulation, and potential macrophage identity loss consistent with ferroptosis vulnerability, genome instability, paradoxical immun...

Hye Jin Kim, Ji Won Park, Seon-Min Lee et al. · Applied Biological Chemistry · 0 citations