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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Shan Guan

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Aug 2026

Tc17-driven antibody-independent mucosal immunity is critical for protection against extracellular bacterial pneumonia

It is shown that protective immunity conferred by mucosal mRNA vaccines (but not parenteral) require neither serum IgG nor airway secretory IgA, but instead depends on a previously unrecognized lung-resident CD8⁺IL-17⁺ T-cells (Tc17) that rapidly recruits neutrophils/macrophages to eliminate bacteria.

Yuheng Liu, Jingjing Zhang, Zhi-Fu Chen et al. · 0 citations
Open access Jul 2026

Deoxyribonucleotide incorporation reshapes mRNA design beyond canonical ribonucleotide boundaries

These findings identify nucleotide class composition as a previously unrecognized parameter governing IVT-mRNA function and establish hybrid ribonucleotide-deoxyribonucleotide backbone engineering as a versatile strategy to expand the chemical space for next-generation mRNA therapeutics.

Xiaoyan Ding, Riu Liao, G. Bampi et al. · 0 citations

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