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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Shanmei Du

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Review Sep 2026

Protein-protein interactions as therapeutic targets in breast cancer: integrated computational and experimental advances, mechanisms and clinical translation

This review systematically summarizes the core regulatory mechanisms of PPIs in breast cancer, focusing on neomorphic interactions (neoPPIs) and hypomorphic interactions (hypoPPIs) induced by driver mutations, and dissecting their regulatory effects on key pathways such as apoptotic pathways, DNA damage repair, and hor...

Kui Liu, Yong Yang, Hong Yang et al. · 0 citations

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