Author

Shao-Yong Pei

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Review Open access Aug 2026

AMPK-Orchestrated Metabolic Reprogramming in Some Flavivirus Infections: Mechanisms and Therapeutic Opportunities

5′-Adenosine monophosphate-activated protein kinase (AMPK) is the principal cellular energy sensor that coordinates metabolic adaptation by balancing anabolic and catabolic pathways in response to energic stress. Beyond its canonical role in maintaining energy homeostasis, AMPK has emerged as a central regulator of hos...

Kaci Craft, Imaan Muhammad, Shao-Yong Pei et al. · Viruses · 0 citations

Open access Jul 2026

Hepatitis C Virus Remodels Lipid Droplets to Promote Mitochondrial Fatty Acid Accumulation and Metabolic Activation

This study shows that hepatitis C virus dynamically remodels lipid droplets, causing an early increase in lipid storage followed by droplet enlargement and mobilization of fatty acids during later infection, and Lipid hydrolysis and mitochondrial fatty acid trafficking therefore represent potential host-directed target...

Imaan Muhammad, Kaci Craft, Shao-Yong Pei et al. · bioRxiv · 0 citations