HSPD1 promotes neuroblastoma by augmenting MYCN expression
It is shown that HSPD1 depletion in MYCN-amplified NB cells led to reduced mitochondrial translation, MYCN expression, and tumorigenesis in vitro and in vivo and establishes HSPD1 as a promising target for the treatment of MYCN-amplified NB.
Shatha S. Alassam, Dinesh Babu Manikandan, Hila Ben-David et al.
· bioRxiv · 0 citations