Taurine is a functional regulator of transthyretin; implication in transthyretin-induced hypothyroidism and amyloidosis
Transthyretin (TTR) is a homo-tetrameric, 55 kDa, transport protein synthesized mainly in the liver, retinal epithelium, choroid plexus, placental villi and uterus. The main function of TTR is transport of thyroxine (T 4 ) and retinol-binding protein, while it also plays a crucial role in neuroprotection. The binding o...