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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Shijian Huang

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Jul 2026

Chronic Toxic Effects of BDE-47 in C3H/He Mice Following Oral Exposure.

As a persistent organic pollutant (POP), 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) can accumulate through the food chain and enter the human body. Most existing studies have focused on short-term toxicity, with insufficient understanding of its chronic toxicity. In this study, a 6-month chronic exposure model was est...

Wei Deng, Xiao-Jing Liu, Xiaobing Wu et al. · 0 citations
Aug 2026

Chronic BDE-47 Exposure Induces DNA Damage in Hepatocytes: Involvement of Oxidative Stress and CYP1A1/2 Upregulation

BDE-47 exposure induces hepatocellular DNA damage, and its mechanism of action is closely associated with AHR-mediated oxidative stress and CYP1A1/2 upregulation, which offers new experimental evidence to clarify the hepatotoxic and genotoxic mechanisms of BDE-47.

Hua Zhong, Liu Yang, Jieqiu Yang et al. · 0 citations

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