Aug 2026
Quercetin Ameliorates Imatinib-Induced Ovarian Damage by Regulating Mitochondrial Dysfunction and PANoptosis via the RAF1-ERK1/2-Drp1 Axis.
In vitro experiments revealed that IMA induced PANoptosis, characterized by membrane blebbing and swelling, pyknosis, as well as rupture of the nuclear and plasma membranes observed, which suppressed IMA-induced PANoptosis, and improved granulosa cell viability and oocyte quality.
Qing-Hui Li, Min Ji, Yan Zhou et al.
· Free Radical Biology & Medic... · 0 citations