Crosstalk among Wnt, Notch, EGF/ErbB, and BMP signaling pathways in intestinal stem cell fate
Background Intestinal stem cell (ISC) proliferation and differentiation are tightly regulated by signaling crosstalk to maintain epithelial homeostasis. Objectives This review synthesizes current evidence on the roles and interactions of Wnt, Notch, EGF/ErbB, and BMP pathways in governing ISC maintenance, self-renewal,...