Renal fibrosis is a progressive pathological process underlying chronic kidney disease (CKD), characterized by persistent fibroblast activation and excessive extracellular matrix accumulation. Although integrin-dependent focal adhesion signaling has been implicated in tissue fibrosis, its role in renal fibroblast activ...
Heracleum candicans, a perennial herb of the Heracleum genus in the Umbelliferae family, is naturally distributed in Pakistan, northwestern India, as well as Sichuan and Xizang of China. In the Xizang region, its dried roots have long been utilized as a traditional Tibetan medicine. Ethnopharmacologically, it possesses...
Yunfeng Bai, Juan Li, Shouzhu Xu et al.· Records of Natural Products· 0 citations
This review integrates current insights into the complex interplay among metabolic stress, mitochondrial injury, and cellular senescence in Diabetic cardiomyopathy and highlights promising directions for mechanism-based interventions aimed at combating diabetic cardiac remodeling.
Ting Ye, Dong-Lin Yang, Xinrui Chang et al.· Cardiovascular Drugs and The...· 0 citations
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