Transcriptomic profiling of human iPSC-derived Schwann-like cells reveals NF2-regulated gene regulatory networks
Schwann cells are vital to development and maintenance of the peripheral nervous system, and their dysfunction has been implicated in a range of neurological and neoplastic disorders, including NF2 -related schwannomatosis ( NF2 -SWN). We have developed a human induced pluripotent stem cells (hiPSCs) model for...