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Review Open access Aug 2026

Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms

γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melan...

Si-Mo Du, Anika Jallorina, Toru Yoshino et al. · 0 citations
Review Open access Aug 2026

Immune Dysregulation, Compartment-Specific Biology, and Therapeutic Biomarkers in Mycosis Fungoides and Sézary Syndrome

Cutaneous T-cell lymphoma (CTCL), including mycosis fungoides (MF) and Sézary syndrome (SS), is defined by malignant CD4+ T-cell clones that evolve within and remodel the skin and systemic immune compartments. For disease biology and immune remodeling, we prioritize evidence from human primary samples; for therapeutic...

Tian-Tian Zhang, Wei-Li Xue, Si-Mo Du et al. · 0 citations

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