Author

Silvio C. E. Tosatto

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Preprint Aug 2026

APICURON: a reactive infrastructure for credit attribution across distributed research data ecosystems

Data-driven biology relies on structured knowledge generated by expert biocurators, yet this work remains largely unrecognized in traditional academic assessments. To bridge this gap, we present the updated APICURON platform, a credit-attribution infrastructure that formally acknowledges these scientific contributions....

Adel Bouhraoua, Mehdi Zoubiri, Gavin Farrell et al. · 0 citations

Preprint Sep 2026

Making Models That Matter: How to Build Trustworthy and Useful Systems Biology Models

Computational models supporting mechanistic understanding of (complex) biological systems, systems behaviour prediction, and experimental design are becoming more and more embedded in research on complex biological systems. Reuse and refinement of models, rather than continuous reinvention, is becoming increasingly imp...

John M. Hancock, Mihail Anton, Frank T. Bergmann et al. · 0 citations

#protein folding Review Open access Sep 2026

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

This review addresses the amyloid aggregation of pVHL, the factors contributing to this behavior, the correlation between protein aggregation and cellular dormancy, and potential therapeutic strategies that bridge protein aggregation and oncology.

L. Abad, Silvio C. E. Tosatto, E. Leonardi · Molecular Oncology · 0 citations