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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Sophie S. Jang

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Open access Aug 2026

Receptor-tethered orthogonal IL-2 enhances regulatory T cell therapy

Tregs engineered with an orthogonal IL-2 tethered to its receptor persisted without exogenous IL-2 and exhibited superior therapeutic efficacy in a mouse model of type 1 diabetes.

Alyssa C. Indart, Huiyun Lyu, V. Nguyen et al. · 0 citations

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