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Author

Stefan Bittner

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Open access Aug 2026

Exploring serum biomarkers in paediatric psychiatry: the impact of NfL and GFAP

The findings suggest that neuroaxonal and astrocytic stress is a component of adolescent psychopathology, particularly in AN, and sNfL appears sensitive to starvation-related neurobiological changes, with levels normalizing alongside weight restoration.

Marc Pawlitzki, L. Masanneck, L. Schlarbaum et al. · 0 citations
Jan 2026

Neurofilament-Leichtkette (sNfL) als Instrument zur Beurteilung der Krankheitsaktivität und des Therapieansprechens bei Multipler Sklerose (MS)

This review addresses measurement methods (SiMoA, automated platforms), pre-analytics/matrix effects, and central confounders (esp. age, BMI/volume of distribution, renal function, intercurrent events), emphasizing standardization via age- and BMI-corrected reference data using Z-scores or percentiles.

Hernan Inojosa, K. Akgün, L. Masanneck et al. · 0 citations
Review Aug 2026

Immune-mediated excitotoxicity in brain disorders.

The concept of excitotoxicity is extended beyond glutamate receptor overactivation to include innate and adaptive immune pathways, introducing the framework of immune-mediated excitotoxicity and defining three hallmarks - feedback, stressor and chronicity - as organizing principles of this paradigm.

Josef Shin, C. Vogelaar, Stefan Bittner et al. · 0 citations

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