The findings suggest that neuroaxonal and astrocytic stress is a component of adolescent psychopathology, particularly in AN, and sNfL appears sensitive to starvation-related neurobiological changes, with levels normalizing alongside weight restoration.
Marc Pawlitzki, L. Masanneck, L. Schlarbaum et al.· Translational Psychiatry· 0 citations
This review addresses measurement methods (SiMoA, automated platforms), pre-analytics/matrix effects, and central confounders (esp. age, BMI/volume of distribution, renal function, intercurrent events), emphasizing standardization via age- and BMI-corrected reference data using Z-scores or percentiles.
Hernan Inojosa, K. Akgün, L. Masanneck et al.· Fortschritte der Neurologie...· 0 citations
The concept of excitotoxicity is extended beyond glutamate receptor overactivation to include innate and adaptive immune pathways, introducing the framework of immune-mediated excitotoxicity and defining three hallmarks - feedback, stressor and chronicity - as organizing principles of this paradigm.
Josef Shin, C. Vogelaar, Stefan Bittner et al.· Nature reviews. Immunology· 0 citations
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