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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Stephen M. Kaminsky

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2 papers indexed here

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Oct 2026

Complement Activation Within Minutes Following Systemic Administration of AAV in the Presence of AAV Immunity.

A challenge of adeno-associated virus (AAV)-mediated gene therapy is the high prevalence of preexisting anticapsid antibodies, which can reduce vector efficacy and, after high-dose systemic administration, promote formation of antibody-vector complexes that activate complement. Complement-mediated toxicities reported a...

A. Caragiulo, J. Rosenberg, B. De et al. · 0 citations
#protein folding Open access Oct 2026

Serotype-Tailored Midstream and Downstream Operations to Advance the Manufacturing of Adeno-Associated Viral Vectors.

Adeno-associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized. This study...

Arianna Minzoni, Shriarjun Shastry, Eduardo Barbieri et al. · 0 citations

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